• Nifedipine disturbs fetal cardiac function during hypoxemia in a chronic sheep model at near term gestation 

      Alanne, Leena; Bhide, Amarnath Govind; Lantto, Juulia; Huhta, Heikki; Kokki, Merja; Haapsamo, Mervi; Acharya, Ganesh; Rasanen, Juha (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11)
      Background: Nifedipine is a widely used drug in pregnancies complicated by maternal hypertensive disorders that can be associated with placental insufficiency and fetal hypoxemia. The evidence regarding fetal myocardial responses to nifedipine in hypoxemia is limited.<p> <p>Objective: We hypothesized that nifedipine would not impair fetal sheep cardiac function under hypoxemic environment. In ...
    • Prostaglandin insert dinoprostone versus trans-cervical balloon catheter for outpatient labour induction: A randomised controlled trial of feasibility (PROBIT-F) 

      Bhide, Amarnath Govind; Sedgwick, Philip; Barrett, Barbara; Cupples, Georgina; Coates, Rose; Goode, Rosie; Linton, Sandra; McCourt, Christine (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-15)
      <i>Background</i> - The aim was to assess the feasibility of conducting a randomised controlled trial (RCT) of induction of labour comparing use of two methods in the outpatient setting.<p> <p><i>Methods</i> - An open-label feasibility RCT was conducted in two UK maternity units from October 2017 to March 2019. Women aged ≥ 16 years, undergoing induction of labour (IOL) at term, with intact ...